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Literature summary for 3.4.24.87 extracted from

  • Soejima, K.; Nakamura, H.; Hirashima, M.; Morikawa, W.; Nozaki, C.; Nakagaki, T.
    Analysis on the molecular species and concentration of circulating ADAMTS13 in blood (2006), J. Biochem., 139, 147-154.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
W688X6-1 the monoclonal antibody W688X6-1 shows dose-dependent inhibitory activity toward ADAMTS13-mediated hydrolysis Homo sapiens
WH2-22-1A the monoclonal antibody WH2-22-1A shows dose-dependent inhibitory activity toward ADAMTS13-mediated hydrolysis Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
full-length form, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HiLoad Superdex 200 gel filtration Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fluorescence resonance energy transfer substrate-von Willebrand factor 73 + H2O
-
Homo sapiens ?
-
?
von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
Homo sapiens
von Willebrand factor-cleaving protease
-
Homo sapiens
VWF cleaving protease
-
Homo sapiens
VWF-CP
-
Homo sapiens