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Literature summary for 3.4.24.87 extracted from

  • Plaimauer, B.; Scheiflinger, F.
    Expression and characterization of recombinant human ADAMTS-13 (2004), Semin. Hematol., 41, 24-33.
    View publication on PubMed

Application

Application Comment Organism
medicine ADAMTS-13 is deficient in congenital thrombotic thrombocytopenic purpura and inhibited in aquired thrombotic thrombocytopenic purpura. The availability of recombinant ADAMTS-13 raises the prospect of developing a recombinant substitution therapy to improve thrombotic thrombocytopenic purpura treatment and allows present diagnostic assays to be simplified Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O cleavage of Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ADAMTS-13
-
Homo sapiens