Application | Comment | Organism |
---|---|---|
medicine | ADAMTS-13 is deficient in congenital thrombotic thrombocytopenic purpura and inhibited in aquired thrombotic thrombocytopenic purpura. The availability of recombinant ADAMTS-13 raises the prospect of developing a recombinant substitution therapy to improve thrombotic thrombocytopenic purpura treatment and allows present diagnostic assays to be simplified | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | cleavage of Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS-13 | - |
Homo sapiens |