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Literature summary for 3.4.24.87 extracted from

  • Arai, S.; Allan, C.; Streiff, M.; Hutchins, G.M.; Vogelsang, G.B.; Tsai, H.M.
    Von Willebrand factor-cleaving protease activity and proteolysis of von Willebrand factor in bone marrow transplant-associated thrombotic microangiopathy (2001), Hematol. J., 2, 292-299.
    View publication on PubMed
Search for more literature for 3.4.24.87

Application

Application Comment Organism
medicine analysis of vWF protease and vWF multimeric distribution are valuable tools in making the distinction between bone marrow transplant-associated thrombotid microangiopathy and thrombotic thrombocytopenic pupura Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular plasma Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
proteins + H2O Homo sapiens
-
 peptides
-
 ?
von Willebrand factor + H2O Homo sapiens decrease of the multimeric pattern of enzyme and decreased activity results in bone marrow transplant-associated thrombotid microangiopathy ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
proteins + H2O
-
 Homo sapiens peptides
-
 ?
von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?
von Willebrand factor + H2O decrease of the multimeric pattern of enzyme and decreased activity results in bone marrow transplant-associated thrombotid microangiopathy Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
M12.241 Merops-ID Homo sapiens
von Willebrand factor-cleaving protease
-
 Homo sapiens
vWF protease
-
 Homo sapiens