Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus anthracis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Synonyms | Comment | Organism |
---|---|---|
anthrax lethal factor | - |
Bacillus anthracis |
anthrax lethal toxin | - |
Bacillus anthracis |
LeTx | - |
Bacillus anthracis |
General Information | Comment | Organism |
---|---|---|
physiological function | anthrax lethal toxin is a virulence factor of Bacilillus anthracis that is a bivalent toxin, containing lethal factor and protective Ag proteins, which causes cytotoxicity and altered macrophage function. Anthrax lethal toxin exposure results in early K+ efflux from macrophages associated with caspase-1 activation and increased interleukin-1beta release | Bacillus anthracis |