Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the enzyme can cut normal prion proteins from the surface of neurons | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | O35598 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
forebrain | - |
Mus musculus | - |
neuron | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme can cut normal prion proteins from the surface of neurons | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
ADAM10 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme depletion in forebrain neurons leads to posttranslational increase of cellular prion protein levels | Mus musculus |
physiological function | the enzyme is a potent modulator of prion disease | Mus musculus |