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Literature summary for 3.4.24.81 extracted from

  • Malinverno, M.; Carta, M.; Epis, R.; Marcello, E.; Verpelli, C.; Cattabeni, F.; Sala, C.; Mulle, C.; Di Luca, M.; Gardoni, F.
    Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage (2010), J. Neurosci., 30, 16343-16355.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.81

Inhibitors

Inhibitors Comment Organism Structure
Tissue inhibitor of metalloproteinase-1
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
synapse
-
 Mus musculus 45202
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
 Mus musculus
-
neuron
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-cadherin + H2O ADAM10/SAP97 interaction is required for ADAM10-mediated cleavage of synaptic N-cadherin Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase 10
-
 Mus musculus
ADAM10
-
 Mus musculus

General Information

General Information Comment Organism
physiological function ADAM10 localization and activity at synapse regulate excitatory synapses through N-cadherin cleavage, influence spine morphology, subunit composition and function of synaptic AMPA receptors Mus musculus