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Literature summary for 3.4.24.81 extracted from

  • Allinson, T.M.; Parkin, E.T.; Condon, T.P.; Schwager, S.L.; Sturrock, E.D.; Turner, A.J.; Hooper, N.M.
    The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein (2004), Eur. J. Biochem., 271, 2539-2547.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information 4-aminophenylmercuric acetate does not stimulate the shedding of beta-amyloid precursor protein Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
SH-SY5Y cell
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
ADAM10 does not cleave angiotensin-converting enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-amyloid precursor protein + H2O
-
Homo sapiens sAPP-alpha fragment + C-terminal fragment
-
?

Synonyms

Synonyms Comment Organism
ADAM10
-
Homo sapiens