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Literature summary for 3.4.24.80 extracted from

  • Li, X.; Ma, Z.; Wang, H.; Ren, L.; Zhang, D.; Liang, W.; Zhang, G.; Zhang, J.; Yu, D.; Fang, X.
    Screening, identification, and characterization of an affinity peptide specific to MT1-MMP and its application in tumor imaging (2019), Bioconjug. Chem., 30, 1507-1517 .
    View publication on PubMed
Search for more literature for 3.4.24.80

Application

Application Comment Organism
analysis screening, identification, and characterization of affinity peptides, AF7p and Cy5.5-HS7, specific to MT1-MMP and application in tumor imaging, overview. Feasibility of using the subtraction biopanning strategy to screen the affinity peptide targeting MT-loop regions and HS7 is a superior probe for noninvasively imaging MT1-MMP expression in MT1-MMP-positive tumor models. Usage of HS7 in early diagnosis of tumors and in peptide-mediated drugs Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P50281
-
-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell
-
 Homo sapiens
-
HT-1080 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
membrane type-1 matrix metalloproteinase
-
 Homo sapiens
MT1-MMP
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function enzyme MT1-MMP plays a crucial role in many physiological and pathological processes, especially in tumor invasion and metastasis Homo sapiens