Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Homo sapiens | 9986 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
54000 | - |
x * 54000, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Type I collagen + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P50281 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
infectious granuloma cell | - |
Homo sapiens | - |
monocyte | - |
Homo sapiens | - |
sputum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Type I collagen + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 54000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
membrane type 1 matrix metalloproteinase | - |
Homo sapiens |
MMP-14 | - |
Homo sapiens |
MT1-MMP | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | in patients with tuberculosis, induced sputum enzyme mRNA levels are increased 5.1fold compared with matched controls. Mycobacterium tuberculosis infection of primary human monocytes increases enzyme surface expression 31.7fold and gene expression 24.5fold | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is critical to monocyte migration | Homo sapiens |