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Literature summary for 3.4.24.80 extracted from

  • Birukawa, N.; Murase, K.; Sato, Y.; Kosaka, A.; Yoneda, A.; Nishita, H.; Fujita, R.; Nishimura, M.; Ninomiya, T.; Kajiwara, K.; Miyazaki, M.; Nakashima, Y.; Ota, S.; Murakami, Y.; Tanaka, Y.; Minomi, K.; Tamura, Y.; Niitsu, Y.
    Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth (2014), J. Biol. Chem., 289, 20209-20221.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.80

Inhibitors

Inhibitors Comment Organism Structure
tissue inhibitor of metalloproteinase 2
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
 x * 56000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pro-MMP-2 + H2O Homo sapiens
-
 MMP-2 + MMP-2 propeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P50281
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pro-MMP-2 + H2O
-
 Homo sapiens MMP-2 + MMP-2 propeptide
-
 ?
Type I collagen + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 56000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
membrane type 1 matrix metalloproteinase
-
 Homo sapiens
MT1-MMP
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function activated hepatic stellate cells require membrane type 1 matrix metalloproteinase-cleaved collagen for their survival Homo sapiens