Literature summary for 3.4.24.80 extracted from

Jiang, A.; Lehti, K.; Wang, X.; Weiss, S.J.; Keski-Oja, J.; Pei, D.
Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis (2001), Proc. Natl. Acad. Sci. USA, 98, 13693-13698.

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Protein Variants

Protein Variants	Comment	Organism
additional information	truncation mutant MT1DELTAC with more robust pro-MMP-2 activation and cell surface expression than wild type enzyme, mutant is resistant to increased cell surface expression after concanavalin A treatment	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	transmembrane protein	Homo sapiens	16020	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	role in extracellular matrix remodelling under physiological and pathological conditions	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P50281	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	role in extracellular matrix remodelling under physiological and pathological conditions	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)