Application | Comment | Organism |
---|---|---|
medicine | appropriate jararhagin concentration can have apoptotic and suppressant effects on SK-Mel-28 cells and can be used to develop potential anti-cancer drugs | Bothrops jararaca |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52000, SDS-PAGE | Bothrops jararaca |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararaca | P30431 | - |
- |
Purification (Comment) | Organism |
---|---|
phenyl Superose column chromatography and Mono-Q column chromatography | Bothrops jararaca |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Bothrops jararaca | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 52000, SDS-PAGE | Bothrops jararaca |
General Information | Comment | Organism |
---|---|---|
physiological function | jararhagin 0.03 mg/ml upregulated genes TP53, CDKN1A, CDKN2A, CASP3, CASP5, CASP6, CASP8, and E-CDH in SKMel-28, and genes ITGB6, ITGB7, CASP3, TP53, and CDKN1B in mouse fibroblasts | Bothrops jararaca |