Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Bothrops jararaca | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Bothrops jararaca | |
additional information | the enzyme is a P-III snake venom metalloproteinase | Bothrops jararaca |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrinogen + H2O | Bothrops jararaca | - |
? | - |
? | |
additional information | Bothrops jararaca | the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin, it induces strong pro-inflammatory response increasing the number of rolling leukocytes within capillary vessels, jararhagin induces apoptosis and release of angiostatin-like peptides in human endothelial cells, overview | ? | - |
? | |
von Willebrand factor + H2O | Bothrops jararaca | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararaca | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from venom | Bothrops jararaca |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Bothrops jararaca | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrinogen + H2O | - |
Bothrops jararaca | ? | - |
? | |
Fibrinogen + H2O | bovine substrate | Bothrops jararaca | ? | - |
? | |
additional information | the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin, it induces strong pro-inflammatory response increasing the number of rolling leukocytes within capillary vessels, jararhagin induces apoptosis and release of angiostatin-like peptides in human endothelial cells, overview | Bothrops jararaca | ? | - |
? | |
von Willebrand factor + H2O | - |
Bothrops jararaca | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bothrops jararaca |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.3 | - |
assay at | Bothrops jararaca |