Application | Comment | Organism |
---|---|---|
medicine | treatment of occlusive thrombi | Agkistrodon contortrix |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | complete and rapid inhibition | Agkistrodon contortrix | |
1,10-phenanthroline | - |
Bothrops neuwiedi | |
DTT | - |
Agkistrodon contortrix | |
EDTA | - |
Agkistrodon contortrix | |
EDTA | - |
Bothrops neuwiedi | |
EDTA | - |
Gloydius halys | |
o-phenanthroline | - |
Gloydius halys | |
Tetraethylenepentamine | complete and rapid inhibition | Agkistrodon contortrix |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000000242 | - |
low molecular weight kininogen | - |
Agkistrodon contortrix | |
0.00000113 | - |
His-Thr-Glu-Phe-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000138 | - |
Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val | - |
Agkistrodon contortrix | |
0.00000164 | - |
His-Thr-Glu-Glu-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000247 | - |
His-Thr-Glu-Lys-Phe-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000338 | - |
His-Thr-Glu-Arg-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000391 | - |
His-Thr-Glu-Pro-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000415 | - |
His-Thr-Glu-His-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000528 | - |
His-Thr-Glu-Leu-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000579 | - |
His-Thr-Glu-Lys-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000739 | - |
His-Thr-Glu-Ala-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000832 | - |
His-Thr-Glu-Ser-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.00000937 | - |
His-Thr-Glu-Asn-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.0000654 | - |
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | - |
Agkistrodon contortrix | |
0.000579 | - |
His-Thr-Glu-Lys-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
22520 | - |
calculated molecular weight | Bothrops neuwiedi |
22710 | - |
- |
Agkistrodon contortrix |
22710 | - |
calculated molecular weight | Gloydius halys |
23000 | - |
MALDI-TOF mass spectrometry | Agkistrodon contortrix |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agkistrodon contortrix | - |
subspecies Agkistrodon contortrix contortrix | - |
Bothrops neuwiedi | - |
- |
- |
Gloydius halys | - |
Agkistrodon halys brevicaudus | - |
Purification (Comment) | Organism |
---|---|
hydrophobic interaction high performance liquid chromatography, hydroxyapatite high performance liquid chromatography and cation exchange high performance liquid chromatography | Agkistrodon contortrix |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Gloydius halys | - |
venom | - |
Bothrops neuwiedi | - |
venom | - |
Agkistrodon contortrix | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O | - |
Agkistrodon contortrix | Arg-Pro-Pro-Gly-Phe-Ser-Pro + Phe-Arg | - |
ir | |
Fibrin + H2O | - |
Gloydius halys | ? | - |
? | |
Fibrin + H2O | - |
Bothrops neuwiedi | ? | - |
? | |
Fibrin + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
Fibrinogen + H2O | - |
Gloydius halys | ? | - |
? | |
Fibrinogen + H2O | - |
Bothrops neuwiedi | ? | - |
? | |
Fibrinogen + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Ala-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Arg-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Asn-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Glu-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-His-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Leu-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Ala-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Arg-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Asn-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Glu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-His-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Phe-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Pro-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Lys-Ser-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Phe-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Pro-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
His-Thr-Glu-Ser-Leu-Val-Thr-Ser + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val + H2O | - |
Agkistrodon contortrix | ? | - |
? | |
low molecular weight kininogen + H2O | - |
Agkistrodon contortrix | kallidin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
brevilysin L6 | - |
Gloydius halys |
neuwiedase | - |
Bothrops neuwiedi |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Bothrops neuwiedi |
37 | - |
- |
Agkistrodon contortrix |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | - |
Agkistrodon contortrix | |
0.0086 | - |
low molecular weight kininogen | - |
Agkistrodon contortrix | |
0.09 | - |
Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val | - |
Agkistrodon contortrix | |
0.16 | - |
His-Thr-Glu-Leu-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.2 | - |
His-Thr-Glu-Lys-Phe-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.45 | - |
His-Thr-Glu-Phe-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
0.46 | - |
His-Thr-Glu-Glu-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
1.59 | - |
His-Thr-Glu-Pro-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
1.97 | - |
His-Thr-Glu-Arg-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
2.23 | - |
His-Thr-Glu-Lys-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
3.98 | - |
His-Thr-Glu-Ser-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
5 | - |
His-Thr-Glu-Ala-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
5.19 | - |
His-Thr-Glu-His-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix | |
6.03 | - |
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | - |
Agkistrodon contortrix | |
65.7 | - |
His-Thr-Glu-Asn-Leu-Val-Thr-Ser | - |
Agkistrodon contortrix |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.1 | 7.4 | - |
Agkistrodon contortrix |
7.4 | 8 | - |
Bothrops neuwiedi |
8.5 | 9.5 | - |
Gloydius halys |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Gloydius halys | - |
- |
4.8 |
Bothrops neuwiedi | - |
- |
5.9 |
Agkistrodon contortrix | - |
- |
6.8 |