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Literature summary for 3.4.24.7 extracted from

  • Moon, H.J.; Park, K.S.; Ku, M.J.; Lee, M.S.; Jeong, S.H.; Imbs, T.I.; Zvyagintseva, T.N.; Ermakova, S.P.; Lee, Y.H.
    Effect of Costaria costata fucoidan on expression of matrix metalloproteinase-1 promoter, mRNA, and protein (2009), J. Nat. Prod., 72, 1731-1734.
    View publication on PubMed
Search for more literature for 3.4.24.7

Application

Application Comment Organism
medicine MMP-1 suppressor Costaria costata fucoidan is a potential therapeutic agent for the prevention and treatment of photoaging of the skin Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
quantitative MMP-1 expression analysis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular MMP-1 is secreted Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HaCaT cell immortalized human keratinocyte cells Homo sapiens
-
keratinocyte
-
 Homo sapiens
-
skin
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-1
-
 Homo sapiens
MMP-1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens fucoidan treatment significantly inhibits the expression of MMP-1 down
Homo sapiens UV-B irradiation induces MMP-1 expression and secretion. Inhibitory effects of Costaria costata fucoidan on UVB-induced MMP-1 promoter, mRNA, and protein expression in vitro by 41.8% at 10 ng/ml, 57.7% at 100 ng/ml, and 70% at 0.001 mg/ml compared to UV-B irradiation alone, overview up

General Information

General Information Comment Organism
malfunction MMP-1 is involved in photoaging of the skin Homo sapiens