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Literature summary for 3.4.24.65 extracted from

  • Nenan, S.; Boichot, E.; Planquois, J.M.; Berna, P.; Hitier, S.; Benard, T.; Lagente, V.; Bertrand, C.P.
    Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways (2008), Eur. J. Pharmacol., 579, 374-381.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme induces inflammation in murine airways after direct instillation eliciting the inflammatory response by neutrophil influx, cytokine release, and gelatinase activation, and delayed response by macrophage recruitment, resident alveolar macrophages and recruited neutrophils do not play a role in the delayed macrophage recruitment induced by MMP-12, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme induces inflammation in murine airways after direct instillation eliciting the inflammatory response by neutrophil influx, cytokine release, and gelatinase activation, and delayed response by macrophage recruitment, resident alveolar macrophages and recruited neutrophils do not play a role in the delayed macrophage recruitment induced by MMP-12, overview Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
Metalloelastase
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Homo sapiens
MMP-12
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Homo sapiens