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Literature summary for 3.4.24.65 extracted from

  • Shi, H.; Xu, J.M.; Hu, N.Z.; Wang, X.L.; Mei, Q.; Song, Y.L.
    Transfection of mouse macrophage metalloelastase gene into murine CT-26 colon cancer cells suppresses orthotopic tumor growth, angiogenesis and vascular endothelial growth factor expression (2006), Cancer Lett., 233, 139-150.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
stable expression of MME domains 1 and 2 in enzyme-deficient murine CT-26 colon cancer cells suppresses orthotopic tumor growth, angiogenesis and vascular endothelial growth factor expression, expression analysis and orthotopic animal tumor model study, overview Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
 x * 22000, mature recombinant enzyme without domain I, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
 Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 22000, mature recombinant enzyme without domain I, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
MME
-
 Mus musculus
More the enzyme is a member of the MMP family Mus musculus
mouse macrophage metalloelastase
-
 Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Mus musculus