Application | Comment | Organism |
---|---|---|
medicine | inhibition of MMP-12 may be a potential modality for the treatment of rheumatoid arthritis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibition of MMP-12 may be a potential modality for the treatment of rheumatoid arthritis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
synovial tissue | mainly expressed by inflammatory macrophages in the rhematoid arthritis synovial membrane. Rheumatoid synovial tissue contains higher levels of MMP-12 messenger RNA than does osteoarthritis synovial tissue. Macrophage-derived MMP-12 may play an important role in the destructive process in rheumatoid arthritis | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase 12 | - |
Homo sapiens |