Cloned (Comment) | Organism |
---|---|
molecular cloning of the proteinase domain of MMP12 | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
hexagonal shaped crystals, crystal structure in complex with hydroxamic acid inhibitor, orthorhombic space group I222, unit cells dimensions a : 67.4 A, b : 87.2, c : 169.2 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CGS27023A | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | catalytic zinc ion | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
MMp-12 active enzyme | Homo sapiens |
54000 | - |
MMp-12 proenzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | important role in inflammatory processes contributing to tissue remodelling | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Elastin + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | important role in inflammatory processes contributing to tissue remodelling | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
human macrophage elastase | - |
Homo sapiens |
MMP-12 | - |
Homo sapiens |