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Literature summary for 3.4.24.61 extracted from

  • Chow, K.M.; Csuhai, E.; Juliano, M.A.; St Pyrek, J.; Juliano, L.; Hersh, L.B.
    Studies on the subsite specificity of rat nardilysin (N-arginine dibasic convertase) (2000), J. Biol. Chem., 275, 19545-19551.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0026
-
2-aminobenzoyl-GGFYRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.003
-
2-aminobenzoyl-GGFNRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.003
-
2-aminobenzoyl-GGFYKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0033
-
2-aminobenzoyl-GGFIRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0036
-
2-aminobenzoyl-GGFLRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0039
-
2-aminobenzoyl-GGFYKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.004
-
2-aminobenzoyl-GGFSRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0044
-
2-aminobenzoyl-GGFHRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0048
-
2-aminobenzoyl-GGFLRKHGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0049
-
2-aminobenzoyl-GGFLRKLGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0051
-
2-aminobenzoyl-GGFLRKIGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0051
-
2-aminobenzoyl-GGFLKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0053
-
2-aminobenzoyl-GGFWRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0054
-
2-aminobenzoyl-GGNLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0055
-
2-aminobenzoyl-GGFLRKWGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0057
-
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0057
-
2-aminobenzoyl-GGHLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0061
-
2-aminobenzoyl-GGFARKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0062
-
2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0064
-
2-aminobenzoyl-GGILRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0065
-
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0065
-
2-aminobenzoyl-GGSLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0066
-
2-aminobenzoyl-GGFLRKFGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0067
-
2-aminobenzoyl-GGMLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0072
-
2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0072
-
2-aminobenzoyl-GGFMRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0073
-
2-aminobenzoyl-GGFLKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0074
-
2-aminobenzoyl-GGFIKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0074
-
2-aminobenzoyl-GGALRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0075
-
2-aminobenzoyl-GGFIKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0075
-
2-aminobenzoyl-GGFLRKMGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.008
-
2-aminobenzoyl-GGWLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0083
-
2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0091
-
2-aminobenzoyl-GGLLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0092
-
2-aminobenzoyl-GGVLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0092
-
2-aminobenzoyl-GGYLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0094
-
2-aminobenzoyl-GGFFRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0094
-
2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0095
-
2-aminobenzoyl-GGFVRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0097
-
2-aminobenzoyl-GGFLRKNGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.01
-
2-aminobenzoyl-GGFLRKAGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.0101
-
2-aminobenzoyl-GGFLRKSGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.011
-
2-aminobenzoyl-GGFLRKDGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ metallopeptidase Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-GGALRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 24% at AL and 76% at RK Rattus norvegicus 2-aminobenzoyl-GGA + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGALRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 24% at AL and 76% at RK Rattus norvegicus 2-aminobenzoyl-GGALR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFARKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 65% at AR and 35% at RK Rattus norvegicus 2-aminobenzoyl-GGFA + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFARKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 65% at AR and 35% at RK Rattus norvegicus 2-aminobenzoyl-GGFAR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFFRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at FR Rattus norvegicus 2-aminobenzoyl-GGFF + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFHRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at HR Rattus norvegicus 2-aminobenzoyl-GGFH + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFIKKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 0% at IK and 100% at KK Rattus norvegicus 2-aminobenzoyl-GGFIK + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFIKRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 0% at IK and 100% at KR Rattus norvegicus 2-aminobenzoyl-GGFIK + RVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 0% at IR and 100% at RK Rattus norvegicus 2-aminobenzoyl-GGFIR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at RK Rattus norvegicus 2-aminobenzoyl-GGFIR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFIRRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 0% at IR and 100% at RR Rattus norvegicus 2-aminobenzoyl-GGFIR + RVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLKKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 5% at LL and 95% at KK Rattus norvegicus 2-aminobenzoyl-GGFL + KKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLKKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 5% at LL and 95% at KK Rattus norvegicus 2-aminobenzoyl-GGFLK + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLKRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 1% at LK and 99% at KR Rattus norvegicus 2-aminobenzoyl-GGFL + KRVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLKRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 1% at LK and 99% at KR Rattus norvegicus 2-aminobenzoyl-GGFLK + RVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKAGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 25% at KA and 75% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KAGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKAGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 25% at KA and 75% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + AGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKDGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at KD and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KDGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKDGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at KD and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + DGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKFGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 17% at KF and 83% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KFGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKFGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 17% at KF and 83% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + FGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKHGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 10% at KH and 90% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KHGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKHGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 10% at KH and 90% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + HGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKIGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 19% at KI and 81% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KIGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKIGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 19% at KI and 81% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + IGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKLGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 26% at KL and 74% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KLGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKLGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 26% at KL and 74% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + LGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKMGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 14% at KM and 86% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KMGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKMGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 14% at KM and 86% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + MGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKNGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 24% at KN and 76% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KNGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKNGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 24% at KN and 76% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + NGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKSGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 25% at KS and 75% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KSGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKSGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 25% at KS and 75% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + SGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O percentage cleaved 23% at LR and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFL + RKVGQ-(N-2,4-dinitrophenyl)ethylenediamine
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at FL and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGF + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at LR and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFL + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at FL and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at KV and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at LR and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at KV and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + VGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKWGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 13% at KW and 87% at RK Rattus norvegicus 2-aminobenzoyl-GGFLR + KWGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRKWGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 13% at KW and 87% at RK Rattus norvegicus 2-aminobenzoyl-GGFLRK + WGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 7% at LR and 93% at RR Rattus norvegicus 2-aminobenzoyl-GGFL + RRVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFLRRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 7% at LR and 93% at RR Rattus norvegicus 2-aminobenzoyl-GGFLR + RVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFMRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 29% at MR and 71% at RK Rattus norvegicus 2-aminobenzoyl-GGFM + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFMRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 29% at MR and 71% at RK Rattus norvegicus 2-aminobenzoyl-GGFMR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFNRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at NR Rattus norvegicus 2-aminobenzoyl-GGFN + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFSRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 76% at SR and 24% at RK Rattus norvegicus 2-aminobenzoyl-GGFS + RKVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFSRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 76% at SR and 24% at RK Rattus norvegicus 2-aminobenzoyl-GGFSR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFVRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at RK Rattus norvegicus 2-aminobenzoyl-GGFVR + KVGQ-ethylenediamine-2,4-dinitrophenyl
-
?
2-aminobenzoyl-GGFWRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at WR Rattus norvegicus 2-aminobenzoyl-GGFW + RKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYKKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at YK and 0% at KK Rattus norvegicus 2-aminobenzoyl-GGFYKKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYKRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 64% at YK and 36% at KR Rattus norvegicus 2-aminobenzoyl-GGFY + KRVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYKRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 64% at YK and 36% at KR Rattus norvegicus 2-aminobenzoyl-GGFYK + RVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at YR Rattus norvegicus 2-aminobenzoyl-GGFY + RKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 100% at YR and 0% at RK Rattus norvegicus 2-aminobenzoyl-GGFY + RKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYRRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 65% at YR and 35% at RR Rattus norvegicus 2-aminobenzoyl-GGFY + RRVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGFYRRVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 65% at YR and 35% at RR Rattus norvegicus 2-aminobenzoyl-GGFYR + RVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGHLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 26% at HL and 74% at RK Rattus norvegicus 2-aminobenzoyl-GGH + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGHLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 26% at HL and 74% at RK Rattus norvegicus 2-aminobenzoyl-GGHLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGILRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 56% at IL and 44% at RK Rattus norvegicus 2-aminobenzoyl-GGI + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGILRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 56% at IL and 44% at RK Rattus norvegicus 2-aminobenzoyl-GGILR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGLLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 73% at LL and 27% at RK Rattus norvegicus 2-aminobenzoyl-GGL + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGLLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 73% at LL and 27% at RK Rattus norvegicus 2-aminobenzoyl-GGLLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGMLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 81% at ML and 19% at RK Rattus norvegicus 2-aminobenzoyl-GGM + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGMLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 81% at ML and 19% at RK Rattus norvegicus 2-aminobenzoyl-GGMLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGNLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at NL and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGN + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGNLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 23% at NL and 77% at RK Rattus norvegicus 2-aminobenzoyl-GGNLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGSLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 4% at SL and 96% at RK Rattus norvegicus 2-aminobenzoyl-GGS + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGSLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 4% at SL and 96% at RK Rattus norvegicus 2-aminobenzoyl-GGSLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGVLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 19% at VL and 81% at RK Rattus norvegicus 2-aminobenzoyl-GGV + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGVLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 19% at VL and 81% at RK Rattus norvegicus 2-aminobenzoyl-GGVLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGWLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 18% at WL and 82% at RK Rattus norvegicus 2-aminobenzoyl-GGW + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGWLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 18% at WL and 82% at RK Rattus norvegicus 2-aminobenzoyl-GGWLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGYLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 2% at YL and 98% at RK Rattus norvegicus 2-aminobenzoyl-GGY + LRKVGQ-ethylenediamine-2,4-dinitrophenyl
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2-aminobenzoyl-GGYLRKVGQ-ethylenediamine-2,4-dinitrophenyl + H2O percentage cleaved 2% at YL and 98% at RK Rattus norvegicus 2-aminobenzoyl-GGYLR + KVGQ-ethylenediamine-2,4-dinitrophenyl
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additional information utilization of series of fluorogenic peptides containing the sequence 2-aminobenzoyl-GGX1X2RKX3GQ-ethylenediamine-2,4-dinitrophenyl. Residues at positions X1, X2, and X3 are varied to study effects at the P3, P2, and P29 positions, respectively Rattus norvegicus ?
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Synonyms

Synonyms Comment Organism
N-Arginine dibasic convertase
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Rattus norvegicus
nardilysin
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Rattus norvegicus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.187
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2-aminobenzoyl-GGFYKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.198
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2-aminobenzoyl-GGFIKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.24
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2-aminobenzoyl-GGFLRKDGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.353
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2-aminobenzoyl-GGFSRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.405
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2-aminobenzoyl-GGFYKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.41
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2-aminobenzoyl-GGFVRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.705
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2-aminobenzoyl-GGFWRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
0.953
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2-aminobenzoyl-GGNLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.08
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2-aminobenzoyl-GGFARKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.08
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2-aminobenzoyl-GGFNRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.22
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2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.23
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2-aminobenzoyl-GGFIRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.59
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2-aminobenzoyl-GGFLRKNGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.74
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2-aminobenzoyl-GGFLRKLGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
1.85
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2-aminobenzoyl-GGYLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.04
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2-aminobenzoyl-GGFLRKAGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.04
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2-aminobenzoyl-GGFLRKIGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.16
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2-aminobenzoyl-GGFLKKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.48
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2-aminobenzoyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.59
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2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl and hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.63
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2-aminobenzoyl-GGFYRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.77
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2-aminobenzoyl-GGFLRKMGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.83
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2-aminobenzoyl-GGFFRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
2.94
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2-aminobenzoyl-GGFLRKFGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
3.24
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2-aminobenzoyl-GGVLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
3.88
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2-aminobenzoyl-GGALRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
4.36
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2-aminobenzoyl-GGHLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
4.65
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2-aminobenzoyl-GGFLRKSGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
4.84
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2-aminobenzoyl-GGILRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
4.86
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2-aminobenzoyl-GGFMRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
4.95
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2-aminobenzoyl-GGWLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
5.61
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2-aminobenzoyl-GGFLRKWGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
5.83
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2-aminobenzoyl-GGLLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
6.9
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2-aminobenzoyl-GGFHRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFXRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
7.84
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2-aminobenzoyl-GGMLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
8.53
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2-aminobenzoyl-GGSLRKVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGXLRKVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
9.75
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2-aminobenzoyl-GGFLKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
9.92
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2-aminobenzoyl-GGFLRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
12.09
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2-aminobenzoyl-GGFIKRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
13.69
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2-aminobenzoyl-GGFLRKHGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFLRKXGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
15.73
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2-aminobenzoyl-GGFIRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFIXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus
18.99
-
2-aminobenzoyl-GGFYRRVGQ-ethylenediamine-2,4-dinitrophenyl pH 7.0, hydrolysis of the peptide series 2-aminobenzoyl-GGFYXXVGQ-ethylenediamine-2,4-dinitrophenyl Rattus norvegicus