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Literature summary for 3.4.24.59 extracted from

  • Hervouet, E.; Pecina, P.; Demont, J.; Vojtiskova, A.; Simonnet, H.; Houstek, J.; Godinot, C.
    Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride (2006), Biochem. Biophys. Res. Commun., 344, 1086-1093.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Co2+ specific strong inhibition Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytochrome c oxidase 4 precursor protein + H2O Homo sapiens enzyme inhibition leads to prevention of the normal processing of the precursor of cytochrome c oxidase, i.e. COX, subunit 4 and induced COX degradation, overview mature cytochrome c oxidase + propeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytochrome c oxidase 4 precursor protein + H2O enzyme inhibition leads to prevention of the normal processing of the precursor of cytochrome c oxidase, i.e. COX, subunit 4 and induced COX degradation, overview Homo sapiens mature cytochrome c oxidase + propeptide
-
?
cytochrome c oxidase 4 precursor protein + H2O identification of the MIP recognition site, overview Homo sapiens mature cytochrome c oxidase + propeptide
-
?

Synonyms

Synonyms Comment Organism
MIP
-
Homo sapiens