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Literature summary for 3.4.24.56 extracted from

  • Brush, J.S.; Sonne, O.; Gliemann, J.
    Degradation of the four monoiodoinsulin isomers by the insulin protease of rat liver (1983), Biochim. Biophys. Acta, 757, 269-273.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Insulin + H2O degradation of 4 monoiodoinsulin isomers Rattus norvegicus Hydrolyzed insulin
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Insulin + H2O the insulin protease appears to first degrade insulin to multiple products with molecular sizes slightly smaller than insulin and subsequently to small peptides (e.g. containing tyrosine A-19) and amino acids (e.g. tyrosine A-14, B-16 and B-26) Rattus norvegicus Hydrolyzed insulin
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