Application | Comment | Organism |
---|---|---|
medicine | mucrolysin possesses lethal and hemorrhagic activities, induces coagulation necrosis, bleeding into various organs, especially the heart and stomach | Protobothrops mucrosquamatus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | inhibits lethal and hemorrhagic activities | Protobothrops mucrosquamatus | |
Antivenin | inhibits lethal and hemorrhagic activities | Protobothrops mucrosquamatus | |
EDTA | inhibits lethal and hemorrhagic activities | Protobothrops mucrosquamatus | |
additional information | not inhibited by DFP, p-chloromercuribenzoate or soybean trypsin inhibitor | Protobothrops mucrosquamatus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Protobothrops mucrosquamatus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity, by gel filtraton and ion-exchange column chromatography | Protobothrops mucrosquamatus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Protobothrops mucrosquamatus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ala-Leu + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Dimethylcasein + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Fibrinogen + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Gly-Gly + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Gly-Met + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Gly-Pro + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Gly-Tyr + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
His-Leu + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
insulin B chain + H2O | hydrolyzes Aalpha chain first and then the Bbeta chain | Protobothrops mucrosquamatus | ? | - |
? | |
Leu-Gly + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
Leu-Tyr + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
additional information | does not hydrolyze casein | Protobothrops mucrosquamatus | ? | - |
? | |
Tyr-Leu + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Mucrotoxin A | - |
Protobothrops mucrosquamatus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Protobothrops mucrosquamatus |