Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | + 4 mM Ca2+: 85% inhibition | Bothrops jararaca | |
5,5'-dithiobis(2-nitrobenzoic acid) | 1 mM: 70% inhibition, in presence of 2 mM Ca2+: 30% inhibition | Bothrops jararaca | |
EDTA | 0.1 mM: complete inhibition | Bothrops jararaca | |
additional information | phosphoramidon, leupeptin, epoxysuccinyl derivatives e.g. E-64, Ep-475 or Ep-479, all 0.5 mM, are no inhibitors | Bothrops jararaca |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Bothrops jararaca |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23000 | - |
1 * 23000, Bothrops jararaca, SDS-PAGE | Bothrops jararaca |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararaca | - |
jararaca snake | - |
Purification (Comment) | Organism |
---|---|
partial | Bothrops jararaca |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Bothrops jararaca | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | cleavage of Pro-Phe | Bothrops jararaca | Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu | - |
? | |
Insulin B-chain + H2O | cleavage of Gln4-His, Ser9-His and Ala14-Leu | Bothrops jararaca | Hydrolyzed insulin B-chain | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 23000, Bothrops jararaca, SDS-PAGE | Bothrops jararaca |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bothrops jararaca |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | - |
assay at | Bothrops jararaca |