Any feedback?
Literature summary for 3.4.24.44 extracted from
- Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e (1978), Biochemistry, 17, 3395-3404.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Crotalus atrox |  |
| EDTA | Zn2+ restores | Crotalus atrox | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | metal analysis detects 0.42 mol Ca2+ and 0.05 mol Mg2+ per mol enzyme | Crotalus atrox | |
| Zn2+ | zinc metalloproteinase | Crotalus atrox | |
| Zn2+ | 1 mol zinc/mol enzyme | Crotalus atrox | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 22000 | - |
Crotalus atrox, gel filtration | Crotalus atrox |
| 25000 | - |
Crotalus atrox, minimum MW calculated from zinc content | Crotalus atrox |
| 25700 | - |
1 * 25700, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Basement membranes surrounding capillaries + H2O | Crotalus atrox | together with hemorrhagic toxins a, b, c, d and f responsible for hemorrhage | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Crotalus atrox | - |
Western diamondback rattlesnake | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| additional information | no glycoprotein | Crotalus atrox |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from lyophilized crude venom | Crotalus atrox |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Crotalus atrox | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Basement membranes surrounding capillaries + H2O | together with hemorrhagic toxins a, b, c, d and f responsible for hemorrhage | Crotalus atrox | ? | - |
? | |
| Dimethylcasein + H2O | - |
Crotalus atrox | ? | - |
? | |
| Dimethylhemoglobin + H2O | - |
Crotalus atrox | ? | - |
? | |
| additional information | no hydrolysis of furylacryloyl-L-leucinamide | Crotalus atrox | ? | - |
? | |
| additional information | no hydrolysis of native collagens | Crotalus atrox | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 25700, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
