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Literature summary for 3.4.24.42 extracted from

  • Bjarnason, J.B.; Tu, A.T.
    Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e (1978), Biochemistry, 17, 3395-3404.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
Crotalus atrox
EDTA
-
Crotalus atrox

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloproteinase Crotalus atrox
Zn2+ 0.86 mol zinc/mol enzyme Crotalus atrox

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
amino acid composition Crotalus atrox
20500
-
Crotalus atrox, isozyme Ht-c, gel filtration Crotalus atrox
21000
-
Crotalus atrox, isozyme Ht-d, gel filtration Crotalus atrox
27900
-
Crotalus atrox, minimal MW calculated from zinc content Crotalus atrox

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Basement membranes surrounding capillaries + H2O Crotalus atrox together with hemorrhagic toxins a, b, e and f responsible for hemorrhage ?
-
?
Basement membranes surrounding capillaries + H2O Crotalus atrox less potent hemorrhagic toxins of Crotalus atrox venom ?
-
?

Organism

Organism UniProt Comment Textmining
Crotalus atrox
-
Western diamondback rattlesnake
-

Purification (Commentary)

Purification (Comment) Organism
from lyophilized crude venom Crotalus atrox

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Crotalus atrox
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Basement membranes surrounding capillaries + H2O together with hemorrhagic toxins a, b, e and f responsible for hemorrhage Crotalus atrox ?
-
?
Basement membranes surrounding capillaries + H2O less potent hemorrhagic toxins of Crotalus atrox venom Crotalus atrox ?
-
?