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Literature summary for 3.4.24.41 extracted from

  • Fox, J.W.; Bjarnason, J.B.
    Atrolysin B (2004), Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 670-671.
No PubMed abstract available

Application

Application Comment Organism
medicine less potent hemorrhagic toxin, degradation of the basement membrane structure surrounding capillaries in muscle tissue Crotalus atrox

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline inhibits proteolytic and hemorrhagic activities Crotalus atrox
EDTA inhibits proteolytic and hemorrhagic activities Crotalus atrox

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
SDS-PAGE Crotalus atrox

Organism

Organism UniProt Comment Textmining
Crotalus atrox
-
-
-

Purification (Commentary)

Purification (Comment) Organism
by ion-exchange chromatography and gel filtration Crotalus atrox

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Crotalus atrox
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Dimethylcasein + H2O
-
Crotalus atrox ?
-
?
Fibrinogen + H2O
-
Crotalus atrox ?
-
?
Gelatin + H2O
-
Crotalus atrox ?
-
?
additional information no signficant degradation of fibrin Crotalus atrox ?
-
?
o-aminobenzoyl-Ala-Gly-Leu-Ala-nitrobenzylamide + H2O
-
Crotalus atrox o-aminobenzoyl-Ala-Gly-Leu + Ala-nitrobenzylamide
-
?
Oxidized insulin B-chain + H2O
-
Crotalus atrox ?
-
?

Synonyms

Synonyms Comment Organism
Hemorrhagic toxin b
-
Crotalus atrox
HT-b
-
Crotalus atrox