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Literature summary for 3.4.24.40 extracted from

  • Shanks, R.; Stella, N.; Hunt, K.; Brothers, K.; Zhang, L.; Thibodeau, P.
    Identification of SlpB, a cytotoxic protease from Serratia marcescens (2015), Infect. Immun., 83, 2907-2916.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.40

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Serratia marcescens

Inhibitors

Inhibitors Comment Organism Structure
alkaline protease inhibitor
-
 Serratia marcescens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-
Serratia marcescens PIC3611
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Serratia marcescens

Synonyms

Synonyms Comment Organism
SlpB
-
 Serratia marcescens

Expression

Organism Comment Expression
Serratia marcescens secretion of SlpB requires type I secretion protein LipD up

General Information

General Information Comment Organism
malfunction strain K904 with deletion of both prtS and slpB genes is defective in secreted protease activity and cytotoxicity to human cell lines Serratia marcescens
physiological function the enzyme exhibits cytotoxicity to airway and ocular cell lines in vitro Serratia marcescens