Cloned (Comment) | Organism |
---|---|
gene MMP9, quantitative RT-PCR enzyme expression analysis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
isovitexin | interacts with enzyme residues Glu241, Ala242, Pro255, Pro254, Thr251, Leu222, Tyr248, Arg241, Met247, His226, and Glu227, binding structure analysis, and modeling, overview | Homo sapiens | |
additional information | Ficus deltoidea leaf extract inhibits matrix metalloproteinase-2, 8 and 9, molecular docking, molecular dynamics, molecular dynamic simulation analysis, overview. Computational docking analysis reveals that vitexin and isovitexin binds to the active site of the three tested MMPs | Homo sapiens | |
N-isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid | NNGH | Homo sapiens | |
vitexin | interacts with enzyme residues Gly186, Pro246, His236, Met247, Tyr248, Val223, and Leu188, binding structure analysis, and modeling, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc-dependent metalloproteinase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14780 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Homo sapiens | - |
EAhy 926 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-9 | - |
Homo sapiens |
MMP-9 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |