Literature summary for 3.4.24.35 extracted from

Joo, S.H.; Kwon, K.J.; Kim, J.W.; Kim, J.W.; Hasan, M.R.; Lee, H.J.; Han, S.H.; Shin, C.Y.
Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells (2010), Neurosci. Lett., 469, 352-356.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
astrocyte	-	Rattus norvegicus	-
glial cell	-	Rattus norvegicus	-
primary cell	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Gelatin + H2O	-	Rattus norvegicus	?	-	?

Synonyms

Synonyms	Comment	Organism
matrix metalloproteinase-9	-	Rattus norvegicus
MMP-9	-	Rattus norvegicus

Expression

Organism	Comment	Expression
Rattus norvegicus	monomeric alpha-synuclein dose-dependently increases MMP-9 activity as well as mRNA level from cultured rat primary astrocytes and microglial cells (about 3fold stimulation at 200 nM). Same concentration of alpha-synuclein aggregates do not induce MMP-9 activity	up

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Release 2023.1 (January 2023)