Literature summary for 3.4.24.35 extracted from

Chotikavanich, S.; de Paiva, C.S.; Li, d.e..Q.; Chen, J.J.; Bian, F.; Farley, W.J.; Pflugfelder, S.C.
Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome (2009), Invest. Ophthalmol. Vis. Sci., 50, 3203-3209.

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Activating Compound

Activating Compound	Comment	Organism	Structure
4-amino phenylmercuric acetate	pro-MMP-9 is activated with 1 mM 4-amino phenylmercuric acetate in assay buffer at 37°C for 1.5 h	Homo sapiens

Application

Application	Comment	Organism
medicine	MMP-9 is a potentially useful biomarker for diagnosing, classifying, and monitoring dysfunctional tear syndrome	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
conjunctival epithelium	-	Homo sapiens	-
tear	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
matrix metalloproteinase-9	-	Homo sapiens
MMP-9	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	tear MMP-9 activity is significantly higher in patients with dysfunctional tear syndrome, this activity is associated with increased mRNA expression of MMP-9	up

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Release 2023.1 (January 2023)