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Literature summary for 3.4.24.35 extracted from

  • Huang, Z.; Wang, L.; Meng, S.; Wang, Y.; Chen, T.; Wang, C.
    Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages (2009), Int. J. Cardiol., 146, 153-158.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
92000
-
SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
THP-1 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
Homo sapiens
MMP-9
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens berberine inhibits the expression of MMP-9 at both the mRNA and protein levels in a dose-dependent manner (0.005-0.05 mM) by suppressing the activation of p38 pathway in phorbol 12-myristate 13-acetate-induced macrophages down