Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Elastin + H2O | Mus musculus | - |
? | - |
? | |
Gelatin + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen type I + H2O | - |
Mus musculus | ? | - |
? | |
collagen type II + H2O | - |
Mus musculus | ? | - |
? | |
collagen type IV + H2O | - |
Mus musculus | ? | - |
? | |
collagen type V + H2O | - |
Mus musculus | ? | - |
? | |
collagen type VII + H2O | - |
Mus musculus | ? | - |
? | |
Elastin + H2O | - |
Mus musculus | ? | - |
? | |
Gelatin + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gelatinase B | - |
Mus musculus |
Matrix metalloproteinase 9 | - |
Mus musculus |
MMP-9 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | Borrelia burgdorferi induces the host protease, matrix metalloproteinase 9, the induction of MMP-9 may allow the organism to disseminate and produce local tissue destruction | up |
General Information | Comment | Organism |
---|---|---|
physiological function | matrix metalloproteinase 9 plays a key role in lyme arthritis but not in dissemination of Borrelia burgdorferi. MMP-9 cleavage of type I collagen results in increased monocyte chemoattraction, MMP-9 plays an important role in regulating inflammation in Lyme arthritis, potentially through the cleavage of collagen type I | Mus musculus |