Activating Compound | Comment | Organism | Structure |
---|---|---|---|
4-aminophenylmercuric acetate | APMA activation of MMP-9 affects tissue inhibitor of metalloproteinase-1 binding to the enzyme resulting in the loss of natural enzyme inhibition | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Tissue inhibitor of metalloproteinase-1 | exogenous tissue inhibitor of metalloproteinase-1 has a greater inhibitory effect on endogenously active MMP-9 than on 4-aminophenylmercuric acetate-activated MMP-9 | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
65000 | - |
4-aminophenylmercuric acetate produces not only the 82000 Da active enzyme but also a C-terminal truncated form of approximately 65000 Da with activity comparable to that of the 82000 Da form | Homo sapiens |
82000 | - |
active enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 9 | - |
Homo sapiens |
MMP-9 | - |
Homo sapiens |