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Literature summary for 3.4.24.35 extracted from

  • Garg, P.; Vijay-Kumar, M.; Wang, L.; Gewirtz, A.T.; Merlin, D.; Sitaraman, S.V.
    Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis (2009), Am. J. Physiol. Gastrointest. Liver Physiol., 296, G175-G184.
    View publication on PubMedView publication on EuropePMC
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
104000
-
 gel filtration Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen type IV + H2O Mus musculus
-
 ?
-
 ?
Gelatin + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen type IV + H2O
-
 Mus musculus ?
-
 ?
Gelatin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
 Mus musculus
MMP-9
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus MMP-9 is upregulated during inflammatory bowel disease, MMP-9 activity is highly upregulated in wild type mice treated with dextran sodium sulfate, Salmonella typhimurium, or trinitrobenzene sulfonic acid up

General Information

General Information Comment Organism
malfunction MMP-9 knockout mice are resistant to dextran sodium sulfate-, Salmonella typhimurium-, or trinitrobenzene sulfonic acid-induced colitis Mus musculus
physiological function epithelial-derived MMP-9 is an important mediator of tissue injury in colitis Mus musculus