Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.35 extracted from

  • Bin Hafeez, B.; Adhami, V.M.; Asim, M.; Siddiqui, I.A.; Bhat, K.M.; Zhong, W.; Saleem, M.; Din, M.; Setaluri, V.; Mukhtar, H.
    Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator (2009), Clin. Cancer Res., 15, 452-459.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information Notch1 may be involved in MMP9 activation either by enhancing its expression or by stabilizing the protein Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information Notch1 knockdown decreases MMP9 expression Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
PC-3 cell
-
Homo sapiens
-
prostate cancer cell line
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
92 kDa gelatinase
-
Homo sapiens
92 kDa type IV collagenase
-
Homo sapiens
matrix metallopeptidase 9 gelatinase B
-
Homo sapiens
Matrix metalloproteinase 9
-
Homo sapiens
MMP9
-
Homo sapiens