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Literature summary for 3.4.24.35 extracted from

  • Dragutinovic, V.V.; Radovanovic, N.S.; Izrael-Zivkovic, L.T.; Vrvic, M.M.
    Detection of gelatinase B activity in serum of gastric cancer patients (2006), World J. Gastroenterol., 12, 105-109.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
Homo sapiens
EDTA
-
Homo sapiens
TIMP-1 formation of proMMP-9/TIMP-1 complexes Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Homo sapiens
Zn2+
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
92000
-
2 * 92000, pro-MMP-9, SDS-PAGE Homo sapiens
220000
-
native PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric cancer cell proteolytic activity and expression of gelatinase B in serum of gastric cancer patients and their correlation with the stage of the tumor Homo sapiens
-
serum
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?
Gelatin + H2O gelatin zymography Homo sapiens ?
-
?
N-alpha-benzoyl-arginine p-nitroanilide + H2O i.e. BAPNA Homo sapiens N-alpha-benzoyl-Arg + 4-nitroaniline
-
?

Subunits

Subunits Comment Organism
dimer 2 * 92000, pro-MMP-9, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.3
-
assay at Homo sapiens