Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | MMP-9 is induced in small renal arteries by recombinant human relaxin, up-regulation of 70% | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclic CTT peptide | a gelatinase inhibitor peptide | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
92000 | - |
x * 92000, pro-MMP-9, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | Rattus norvegicus | - |
? | - |
? | |
additional information | Rattus norvegicus | myogenic reactivity, inhibited in small renal arteries isolated from nonpregnant rats treated with recombinant human relaxin, is completely restored by incubation with MMP-9, MMP-9 rather than MMP-2 plays a central role in the vasodilatory effect of short-term relaxin administration, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Long-Evans female rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
renal artery | immunohistochemic analysis | Rattus norvegicus | - |
vascular smooth muscle | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
MMP-9 activity in relaxin-treated and untreated renal artery, overview | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Rattus norvegicus | ? | - |
? | |
Gelatin + H2O | gelatin zymography | Rattus norvegicus | ? | - |
? | |
additional information | myogenic reactivity, inhibited in small renal arteries isolated from nonpregnant rats treated with recombinant human relaxin, is completely restored by incubation with MMP-9, MMP-9 rather than MMP-2 plays a central role in the vasodilatory effect of short-term relaxin administration, overview | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 92000, pro-MMP-9, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-9 | - |
Rattus norvegicus |
MMP-9 | - |
Rattus norvegicus |