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BRENDA support

Literature summary for 3.4.24.35 extracted from

  • Leveque, T.; Le Pavec, G.; Boutet, A.; Tardieu, M.; Dormont, D.; Gras, G.
    Differential regulation of gelatinase A and B and TIMP-1 and -2 by TNFalpha and HIV virions in astrocytes (2004), Microbes Infect., 6, 157-163.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte enzyme expression is slightly induced by HIV and strongly induced by TNF alpha, while matrix metalloproteinase MMP-2 and tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 are only slightly affected. Astrocytes are a major source of enzyme in the inflamed brain Homo sapiens
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