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Literature summary for 3.4.24.35 extracted from

  • Hu, J.; Van den Steen, P.E.; Houde, M.; Ilenchuk, T.T.; Opdenakker, G.
    Inhibitors of gelatinase B/matrix metalloproteinase-9 activity. Comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody (2004), Biochem. Pharmacol., 67, 1001-1009.
    View publication on PubMed
Search for more literature for 3.4.24.35

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 10 mM, 100% inhibition Homo sapiens
D-penicillamine 10 mg/l, 43% inhibition Homo sapiens
EDTA 10 mM, 74% inhibition Homo sapiens
polyhistidine 0.001 mM, 68% inhibition Homo sapiens
REGA-3G12 scFv with (His6)2 monoclonal antibody REGA-3G12 single-chain variable fragment, 0.005 mM, 66% inhibition Homo sapiens
Tissue inhibitor of metalloproteinase-1 1 nM, 88% inhibition Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-NH2 + H2O
-
 Homo sapiens ?
-
 ?
L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-NH2 + H2O
-
 Homo sapiens ?
-
 ?
additional information no substrate: L-Pro-L-Pro(OH)-Gly-L-Gln-Gly-L-Ala(CH3)-L-Thr-Gly-L-Glu-L-Pro(OH)-Gly-CONH2 Homo sapiens ?
-
 ?