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Literature summary for 3.4.24.35 extracted from

  • Chen, E.I.; Li, W.; Godzik, A.; Howard, E.W.; Smith, J.W.
    A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9 (2003), J. Biol. Chem., 278, 17158-17163.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cDNA of the mutated enzyme used to transfect HEK 293 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
E412D site-directed mutagenesis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Purification (Commentary)

Purification (Comment) Organism
catalytic domain of mutated enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ephB1 + H2O
-
Homo sapiens ?
-
?
peptide A13 + H2O
-
Homo sapiens ?
-
?
peptide A13R + H2O
-
Homo sapiens ?
-
?
peptide A3 + H2O
-
Homo sapiens ?
-
?
peptide A34 + H2O
-
Homo sapiens ?
-
?
peptide B74 + H2O
-
Homo sapiens ?
-
?
peptide C15 + H2O non-selective peptide substrate Homo sapiens ?
-
?
peptide C9 + H2O
-
Homo sapiens ?
-
?
peptide m1A11 + H2O non-selective peptide substrate Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
metrix metalloproteinase-9
-
Homo sapiens
MMP-9
-
Homo sapiens