Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Calcium | required | Homo sapiens | |
Zinc | required | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | plays a role in tumor cell invasion and in destruction of cartilage in arthritis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Asp432, Asp433, and His400 residues are important for the activity of gelatinase B, His400 may act as a zinc-binding ligand, Asp432 and Asp433 are probably involved in stabilization of the active site of the enzyme | Homo sapiens | ? | - |
? | |
additional information | plays a role in tumor cell invasion and in destruction of cartilage in arthritis | Homo sapiens | ? | - |
? |