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Literature summary for 3.4.24.24 extracted from

  • Lian, Y.Y.; He, H.H.; Zhang, C.Z.; Li, X.C.; Chen, Y.H.
    Functional characterization of a matrix metalloproteinase 2 gene in Litopenaeus vannamei (2019), Fish Shellfish Immunol., 84, 404-413 .
    View publication on PubMed
Search for more literature for 3.4.24.24

Cloned(Commentary)

Cloned (Comment) Organism
gene LvMMP-2, DNA and amino acid sequence determination and analysis, sequence compariosns and phylogenetic analysis, quantitative real-time RT-PCR enzyme expression analysis Penaeus vannamei

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
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 Penaeus vannamei 5783
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Organism

Organism UniProt Comment Textmining
Penaeus vannamei A0A5H2QHE4 i.e. Penaeus vannamei
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis very high expression Penaeus vannamei
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eyestalk low expression Penaeus vannamei
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gill higher expression Penaeus vannamei
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heart low expression Penaeus vannamei
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hemocyte higher expression Penaeus vannamei
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hepatopancreas
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 Penaeus vannamei
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intestine higher expression Penaeus vannamei
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additional information the enzyme is highly expressed in epidermis, located to endoplasmic reticulum in S2 cells Penaeus vannamei
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muscle low expression Penaeus vannamei
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nerve
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 Penaeus vannamei
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pyloric cecum
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 Penaeus vannamei
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S2 cell
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 Penaeus vannamei
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stomach low expression Penaeus vannamei
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Synonyms

Synonyms Comment Organism
LvMMP-2
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 Penaeus vannamei
Matrix metalloproteinase 2
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 Penaeus vannamei
MMP-2
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 Penaeus vannamei

Expression

Organism Comment Expression
Penaeus vannamei promoter activity of LvMMP-2 is enhanced by LvNRF2 in a ARE site dependent-manner. Overexpression of Lvc-Jun in S2 cells demonstrates that AP-1 is also involved in LvMMP-2 regulation additional information
Penaeus vannamei oxidative stress increases the expression of LvMMP-2 up

General Information

General Information Comment Organism
malfunction knockdown of LvMMP-2 expression decreases shrimp cumulative mortality upon oxidative stress. Knocked-down expression of LvMMP-2 depresse sthe expression of penaeidin2 and beta-defensin. Downregulation of LvMMP-2 suppresses the cumulative mortality of shrimp infected with white spot syndrome virus (WSSV) or with Vibrio alginolyticus Penaeus vannamei
physiological function LvMMP-2 plays a role in innate immunity response. Promoter activity of LvMMP-2 is enhanced by LvNRF2 in a ARE site dependent-manner. Overexpression of Lvc-Jun in S2 cells demonstrates that AP-1 factor c-Jun is also involved in LvMMP-2 regulation Penaeus vannamei