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Literature summary for 3.4.24.24 extracted from
- Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2) (1995), Cancer Res., 55, 2548-2555.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Tissue inhibitor of metalloproteinase-1 | - |
Homo sapiens | |
| Tissue inhibitor of metalloproteinase-2 | - |
Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | activation of progelatinase B is mediated by gelatinase A species that may be localized in the surface of tumor cells and enhance matrix degradation during cancer metastasis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | activation of progelatinase B is mediated by gelatinase A species that may be localized in the surface of tumor cells and enhance matrix degradation during cancer metastasis | Homo sapiens | ? | - |
? | |
| Progelatinase B + H2O | activation to an 82000 MW active form | Homo sapiens | ? | - |
? | |
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