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Literature summary for 3.4.24.24 extracted from

  • LePage, R.N.; Fosang, A.J.; Fuller, S.J.; Murphy, G.; Evin, G.; Beyreuther, K.; Masters, C.L.; Small, D.H.
    Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimers disease (1995), FEBS Lett., 377, 267-270.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
110000 MW cell-surface amyloid protein precursor + H2O amyloid protein precursor of Alzheimer's disease, cleavage to a 1000 MW form of the protein Homo sapiens ?
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