Any feedback?
Literature summary for 3.4.24.24 extracted from
- Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments (1995), J. Biol. Chem., 270, 5872-5876.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0085 | - |
type I collagen | - |
Gallus gallus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Gallus gallus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture medium | from Rous-sarcoma virus-transformed chicken embryo fibroblasts | Gallus gallus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Collagen + H2O | soluble triple helical type I collagen, 3/4- and 1/4-length collagen fragments are formed | Gallus gallus | ? | - |
? |  |
| Collagen + H2O | fibrillar collagen | Gallus gallus | ? | - |
? | |
| Collagen + H2O | no cleavage of interstitial collagens | Gallus gallus | ? | - |
? | |
| Collagen + H2O | denatured collagen | Gallus gallus | ? | - |
? | |
| Type I collagen + H2O | - |
Gallus gallus | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0045 | - |
type I collagen | - |
Gallus gallus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
