Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Brij-35 | activates MMP-7 in a broad concentration range, but inhibits at high concentration | Homo sapiens |
Application | Comment | Organism |
---|---|---|
diagnostics | endometase is putative early biomarker for human carcinomas | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Brij-35 | activates MMP-7 in a broad concentration range, but inhibits at high concentration | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09237 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
7-amino-4-methylcoumaryl-Pro-Lys-Pro-Leu-Ala-Leu-Dap(Dnp)-Ala-Arg-NH2 + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | MMP-7 possesses hydrophobic surface areas around the catalytic site, PDB code 2DDY | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
matrilysin | - |
Homo sapiens |
MMP-7 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
4.6 | - |
pH 7.5, 25°C | Homo sapiens | Brij-35 |