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Literature summary for 3.4.24.23 extracted from

  • Szklarczyk, A.; Conant, K.; Owens, D.F.; Ravin, R.; McKay, R.D.; Gerfen, C.
    Matrix metalloproteinase-7 modulates synaptic vesicle recycling and induces atrophy of neuronal synapses (2007), Neuroscience, 149, 87-98.
    View publication on PubMed
Search for more literature for 3.4.24.23

Localization

Localization Comment Organism GeneOntology No. Textmining
synapse
-
 Homo sapiens 45202
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ a zinc-dependent endopeptidase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens MMP-7 alters the structure and function of presynaptic terminals without affecting neuronal survival, it induces long-lasting inhibition of synaptic vesicular recycling in rat neurons, chronic application results in synaptic atrophy, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09237
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
commercial preparation active, recombinant Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MMP-7 alters the structure and function of presynaptic terminals without affecting neuronal survival, it induces long-lasting inhibition of synaptic vesicular recycling in rat neurons, chronic application results in synaptic atrophy, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-7
-
 Homo sapiens
MMP-7
-
 Homo sapiens
More the enzyme belongs to the zinc-dependent endopeptidases Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens