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Literature summary for 3.4.24.23 extracted from

  • Bilousova, T.V.; Rusakov, D.A.; Ethell, D.W.; Ethell, I.M.
    Matrix metalloproteinase-7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation (2006), J. Neurochem., 97, 44-56.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme influences the morphology of mature dendritic spines, and hence synaptic stability. In hippocampal neuron cultures, enzyme induces the transformation of mature, short mushroom-shaped spines into long, thin filopodia accompanied by dramaitc redistribution of F-actin from spine heads into thick, rope-like structures in the dendritic shaft ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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 recombinant enzyme, commercial preparation
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme influences the morphology of mature dendritic spines, and hence synaptic stability. In hippocampal neuron cultures, enzyme induces the transformation of mature, short mushroom-shaped spines into long, thin filopodia accompanied by dramaitc redistribution of F-actin from spine heads into thick, rope-like structures in the dendritic shaft Homo sapiens ?
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 ?