Literature summary for 3.4.24.23 extracted from

Oneda, H.; Shiihara, M.; Inouye, K.
Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (Matrilysin) (2003), J. Biochem., 133, 571-576.

Search for more literature for 3.4.24.23

Inhibitors

Inhibitors	Comment	Organism	Structure
(-)-catechin-3-gallate	-	Homo sapiens
(-)-epicatechin-3-gallate	-	Homo sapiens
(-)-epigallo-3-catechin gallate	-	Homo sapiens
(-)-gallocatechin-3-gallate	-	Homo sapiens
green tea catechin	-	Homo sapiens
ZnCl2	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(7-methoxycoumarin-4-yl)acetyl-L-Pro-L-Leu-Gly-L-Leu-[N3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]-L-Ala-L-Arg-NH2 + H2O	MOCAc-PLGL(Dpa)AR	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
matrilysin	-	Homo sapiens
Matrix metalloproteinase 7	-	Homo sapiens
MMP-7	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00047	-	(-)-epicatechin-3-gallate	pH 7.5, 25°C	Homo sapiens
0.00106	-	(-)-gallocatechin-3-gallate	pH 7.5, 25°C	Homo sapiens
0.00144	-	(-)-catechin-3-gallate	pH 7.5, 25°C	Homo sapiens
0.00165	-	(-)-epigallo-3-catechin gallate	pH 7.5, 25°C	Homo sapiens

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Release 2023.1 (January 2023)